Response time data for numerical and nonnumerical (letters, months) comparison and ordering tasks (n=36) Includes scores for arithmetic performance and algebra skills.
The prevalence of antibiotic-resistant pathogens has become a major threat to public health, requiring swift initiatives for discovering new strategies to control bacterial infections. Hence, antibiotic stewardship and rapid diagnostics, but also the development, and prudent use, of novel effective antimicrobial agents are paramount. Ideally, these agents should be less likely to select for resistance in pathogens than currently available conventional antimicrobials. The usage of antimicrobial Peptides (AMPs), key components of the innate immune response, and combination therapies, have been proposed as strategies to diminish the emergence of resistance. Herein, we investigated whether newly developed random antimicrobial peptide mixtures (RPMs) can significantly reduce the risk of resistance evolution in vitro to that of single sequence AMPs, using the ESKAPE pathogen Pseudomonas aeruginosa (P. aeruginosa) as a model Gram-negative bacterium. Infections of this pathogen are difficult to treat due the inherent resistance to many drug classes, enhanced by the capacity to form biofilms. P. aeruginosa was experimentally evolved in the presence of AMPs or RPMs, subsequentially assessing the extent of resistance evolution and cross-resistance/collateral sensitivity between treatments. Furthermore, the fitness costs of resistance on bacterial growth were studied, and whole-genome sequencing used to investigate which mutations could be candidates for causing resistant phenotypes. Lastly, changes in the pharmacodynamics of the evolved bacterial strains were examined. Our findings suggest that using RPMs bears a much lower risk of resistance evolution compared to AMPs and mostly prevents cross-resistance development to other treatments, while maintaining (or even improving) drug sensitivity. This strengthens the case for using random cocktails of AMPs in favour of single AMPs, against which resistance evolved in vitro, further providing an alternative to classic antibiotics worth pursuing.
View lessIn order to achieve the objectives of each work package, the Una.Resin project followed a common methodology across work packages: Development of shared strategies, agendas and policies following definition of scope, mapping of policies and assets, stakeholder consultation and identification of barriers and enablers of R&I cooperation Development of an action plan to implement shared priorities Initial implementation via pilot actions Evaluation of pilot actions This dataset relates to phases 3 and 4: “Initial implementation via pilot actions” and “Evaluation of pilot actions”. The pilots were planned considering the learnings of the benchmarking phase described in the dataset “Una.Resin_WP1_T1.2_benchmarking‐questionnaire_20240125” and the co‐creation workshops described in the dataset “Una.Resin_WP1_co_creation workshops_20240129 “. Even if common methodology across work packages was a guideline for us, we did not follow it fully chronologically, but the tasks were overlapping enabling that we could consider the key learnings from the pilots in the Una Europa R&I strategy and roadmap development. Concerning specifically the work done in WP1, the main major tasks of the benchmarking phase were: R&I Strategy Benchmarking including the benchmarking questionnaire and benchmarking of the publicly available strategies of the Una Europa universities; on‐line R&I Strategy Workshop involving academics from all partner universities; One Health SSC Workshop involving academics from the Una Europa One Health focus area; Online Consultation of the Una Europa Community done using Viima platform and done in collaboration with the Una Europa 2030 Strategy process and answers of the eight strategic questions for targeted to the Una Europa partners institutions done also as part of the Una Europa 2030 strategy. All these activities have been described in the Una.Resin WP1 Deliverable 1.1. “Benchmarking R&I Strategies and Priorities for a Joint Una Europa Strategy”. WP1 was working closely with the clusters of research professionals, especially the Research coordination cluster chaired by UH and the Cluster for Public, Private and Third Sector Collaboration (PPTSC) chaired by FUB to understand the relevant structures and processes to build sustainable support for Una Europa research‐collaboration. We also collected insights from the Una Europa focus area self‐steering committees. The pilot 1 was planned and carried out together with the One Health SSC. All the eight Una.Resin project Partner universities were involved either in planning and/or in the implementation of these pilots: University of Edinburgh; University of Helsinki; University of Bologna; Complutense University of Madrid; Freie University Berlin; Katholieke Universiteit Leuven; Jagiellonian University; Université Paris 1 Panthéon‐Sorbonne. Horizon 2020 Una.Resin project Work Package 1 Pilot 1 “Developing a format for supporting systematic collaboration on the Una Europa priority global challenges” (T1.11) Under this pilot we had two separate actions: 1) Una Europa R&I strategy workshop and 2) Piloting a process Horizon Europe Pillar II Call matchmaking. The first part is described in the dataset “Una.Resin_WP1_co_creation workshops_20240129”. In this dataset we provide the key documents of the part “Piloting a process Horizon Europe Pillar II Call matchmaking”. According to the Una.Resin WP1 benchmarking phase and as outcome of the co‐creation workshops and the discussions with the Un Europa focus area self‐steering committees, there is a major interest and unused potential in our alliance regarding European funding, particularly Horizon Europe Pillar II funding. There are existing support service structures at most partner universities, thus there is potential to build systematic and sustainable support for the calls also on Una Europa level and to share each other´s best practices. In this pilot process we identified the enabling and hindering structures, processes, and cultures at the partner universities and at the alliance level. We also shared best practises and tools to create an ideal process. The pilot action was designed and facilitated in close collaboration with the Una Europa Research Coordination Cluster, the Self‐steering committee of the One Health focus area as well as the Una Europa Vzw external funding manager. We also had an honour to have an EC keynote speaker at the first of our two workshop, Research Policy Officer Jean‐Charles Cavitte. He familiarized the participants with EC policy and EU funded research linked to One Health. The whole process from first planning meetings to the evaluation phase lasted from February 2022 until September 2023. The pilot included the following steps: 1) Collecting expressions of interest on‐line using Lyyti platform (https://www.lyyti.com/en/); 2) Identification and briefing of the potential coordinators; 3) On‐line workshop including i) common session highlighting the European goals and the call particularities as well as ii) facilitated group discussion aiming to draft the core idea of the proposal and appointing the core group for the proposal preparation. We used the template created in the R&I strategy workshop (Zoom as a meeting platform and Google Slides for the on‐line canvases); 4) Hybrid (on‐line and on‐site) workshop for the groups of researchers who engaged with proposal preparation (Teams). In this workshop the participants had a change i) to learn about the call particularities and proposal writing in the plenary sessions, ii) get support for the proposal drafting and iii) to participate Una Europa One Health networking event. The workshop was organised in connection to the Una Europa General Assembly; 5) Proposal preparation phase; 6) On‐line evaluation questionnaire after the process (Lyyti platform). In this dataset we provide the key documents to understand the process and to take the learning to future use. Horizon 2020 Una.Resin project Work Package 1 Pilot 2 “Developing a concept for an Una Europa collaboration platform” (Task 1.12) The task was aimed at collecting insights on what a joint platform for collaboration between Una Europa researchers and non‐academic partners should consist of. To develop this concept, a series of consultations and workshops were organized, and a preliminary mapping exercise took place. The key workshops contributing to this task have been presented in the dataset: “Una.Resin_WP1_co_creation workshops_20240129”. In addition, insights were collected from the Una.Resin WPs, Una.Resin Cluster chairs and the self‐steering committees of the Una Europa focus areas. The Research coordination cluster contributed to the concept development in several stages and in particular in RCC workshop in Paris in 2022 and in discussions in Edinburgh in September 2022.
View lessIn order to achieve the objectives of each work package, the Una.Resin project followed a common methodology across work packages: •Development of shared strategies, agendas and policies following definition of scope, mapping ofpolicies and assets, stakeholder consultation and identification of barriers and enablers of R&Icooperation •Development of an action plan to implement shared priorities •Initial implementation via pilot actions •Evaluation of pilot actions In the phase 1 WP1 aimed to understand the relevant policies of the different institutions, providing WPs with essential information to develop shared strategies. The main methods used in this phase were: (1) benchmarking of the strategies and policies including questionnaires, targeted at policy makers, research administration professionals and relevant academics; (2) co-creation workshops for the academic community, targeted mainly at the research professionals and the academic leaders and other researchers in the Una Europa focus areas. These are described in the datasets “Una.Resin_WP1_T1.2_benchmarking-questionnaire_20240125" and “Una.Resin_WP1_co_creation workshops_20240129”. In the second half of the project, the WP1 main tasks were carrying on two pilots described in the dataset “Una.Resin_WP1_T1.11._1.12._Pilots_20240131” and in the end, writing the R&I strategy, the Una Europa R&I Investment Pathway (Annex 1 of the strategy) and the Roadmap to Implementation (Straetgy Annex 2). The strategy writing process included several consultations with the Una Europa leading bodies RSG and BoD, the Una.Resin WPs, Una Europa Vzw, Una.Futura project management as well as consultations with the self-steering groups of the Una Europa focus areas. In addition, the WP1 was working closely with the clusters of research professionals, especially the Research coordination cluster chaired by UH and the Cluster for Public, Private and Third Sector Collaboration (PPTSC) chaired by FUB to understand the relevant structures and processes to build sustainable support for Una Europa research-collaboration. WP1 also consulted the Una Europa Diversity council for diversity in the R&I strategy based on their analysis of the D1.1 in 2022. The council chair also presented the messages to the RSG as part of the R&I strategy preparation process. The Una Europa R&I strategy was developed in close connection to the Una Europa 2030 strategy process and considering the simultaneously accumulated lessons learned from the 1Europe project. In addition, the aims of the Una.Futura project that kicked off in December 2022 were considered in the strategy development. We also discussed with the self-steering committees of the Una Europa focus areas to make sure that the strategies and action plans of them are considered and in line with the Una Europa R&I strategy preparation. Una Europa R&I strategy is not an umbrella strategy for all existing or future R&I strategies of Una Europa partner universities. We outlined that because the Una Europa priority setting had been done already in the Una Europa 2030 process, in the Una Europa R&I strategy we further developed priorities and activities to implement these aims and present in the strategy “strategic areas of actions” referring to the areas, where actions should be implemented to support the research collaboration in Una Europa in the most optimal and effective way. In order to identify these areas, we identified individual actions. Besides the activities identified in the co-creation workshops and WP1 deliverable D1.1. and in the discussions with the Una Europa focus area self-steering committees, we carried out a strategic questionnaire of 16 questions targeted to Una.Resin WP 2-4 leads and co-leads, Una Europa professional cluster chairs and the Una Europa Vzw. In the questionnaire, we asked the colleagues to identify 2-4 themes and individual activities which should be set as strategic priorities when developing services and allocating resources for supporting researcher and/or for institutional or professional development. The answers were based on the Una.Resin aims, outcomes and insights. The questions addressed the priority strategic themes and key stakeholders, processes, actions and resources required to reach the aim. We also asked about the communication and matchmaking needs and the cluster learnings and aims. The roadmap to implementation of the strategic areas of actions aims to establish sustainable links between individual actions driving the R&I collaboration in our Alliance and the ongoing Una.Futura project. Furthermore, the roadmap process aims to identify essential activities where the Alliance has ambition, but which go beyond the ongoing project frameworks. Roadmap phases: Phase I, Identification: Identifying concrete actions that could be taken to achieve our strategic aims as well as a process of structuring these actions in detail according to their level of ambition and required resourcing. This part was carried out by Una.Resin WP1 in a process described above. The next phases: Phase II, Prioritisation and the Phase III, Implementation will take place beyond the duration of Una.Resin. Prioritisation of actions (matrix exercise) at the alliance's highest decision-making level is on-going in early 2024. It sets the frame to Phase three that foresees the implementation of those activities selected as priorities in the previous phase. Actions will be taken either in the framework of Una.Futura through the SSC strategies and action plans or, depending on the nature of action, as a project-independent all-Alliance activity guided by the Una Europa R&I Strategy and the Una Europa 2030 Strategy.
View lessDieser Datensatz enthält Digitalisate der Feldtagebücher der Grabungsstelle "Rotes Haus" (Grabungabschnitt "Mittlere Unterstadt II") in Tall Šēḫ Ḥamad (Syrien) aus den Ausgrabungskampagnen 1992-1995, 1997-2004, 2006, 2008-2010.
The dataset is related to the Horizon 2020 Una.Resin project Work Package 1 Tasks 1.2 and 1.3. It describes the co-creation workshop methods, agendas and outcomes that fed into the preparation of the Una Europa Research & Innovation (R&I) strategy, Task 1.10. R&I roadmap (annex 2 of the WP1 D1.2). and to the Task 1.9. resulting the Una Europa R&I Funding Pathway (annex 1 of the WP1 D1.2). The outcomes also fed into the pilot tasks 1.11. (Horizon Europe Pillar II matchmaking) and 1.12. (Concept for a Una Europa collaboration platform) These workshops were carried out between September 2021 and April 2022 by the University of Helsinki and Freie Universität Berlin. They were targeted to professionals and academics at each of the eight Una Europa universities participating in the project (University of Edinburgh; University of Helsinki; University of Bologna; Complutense University of Madrid; Freie University Berlin; Katholieke Universiteit Leuven; Jagiellonian University; Université Paris 1 Panthéon-Sorbonne) aiming to identify the complementary strengths, opportunities, enablers, and barriers of the research collaboration in this alliance.
View lessThis is an overview of the syntheses and structural conformation of in-house synthesized compounds. These compounds belong to the group of sereoisomers of metabolites of anabolic androgenic steroids and have been used in different studies in our working group.
Der Datensatz enthält Messwerte im fünf Minuten Takt des 'FU- Microclimate network' (FUMiNET) aus dem Berliner Stadtgebiet. Dieses Messnetz wurde kontinuierlich seit dem Jahr 2017 aufgebaut und dient der skalenübergreifenden Erfoschung des Stadtklimas von Berlin, welches durch das BMBF 'Stadtklima im Wandel Projektes' (https://www.uc2-program.org/) gefördert wurde. Die Stationen sind so aufgebaut, dass die Stadtstruktur von Berlin gut abgebildet wird. Gemessen wird die 2m Temperatur und Feuchte. Im Datenpaket sind die Daten des Jahres 2023 enthalten. Zu jeder der Stationen gibt es eine Datei mit gepackten Daten im CSV Format. In einer Gesamtbeschreibung als eine pdf Datei sind die Standorte expliziert beschrieben.
View lessIm BMBF-Förderprojekt „tech4compKI“ intendieren acht Verbundpartner, die Vorteile von individuellem Mentoring mit digitalen Möglichkeiten wie Künstlicher Intelligenz allen Studierenden zur Verfügung zu stellen. Im Projekt entwickelt die TU Dresden eine Mentoring Workbench, ein User Interface mit interaktiven Tools zur Steuerung des Lernprozesses, dazu zählen u. a. eine Timeline, eine Suchfunktion und ein Chatbot. In diesem Kontext wurde eine UX-Design Studie entworfen, um prospektiv zur Verbesserung und Entwicklung der Technologie beizutragen.
Es wurden ein User Flow erstellt und zu dessen Analyse eine quantitative Usability-Umfrage sowie eine qualitative Fokusgruppe durchgeführt. Die Analyse des User Flows ist hilfreich, Problempunkte in der Interaktion mit den Systemkomponenten zu erkennen. Mit dem User Flow und Fragebogen wurden die Benutzererfahrungen individuell erfasst, um datenbasierte Einblicke in die Bedienbarkeit, Nützlichkeit, den erwarteten Zeitaufwand und die allgemeine Zufriedenheit mit der Technologie zu erhalten. Diese Erfahrungen wurden im Rahmen einer gemeinsamen Fokusgruppe eruiert, dabei wurden mit Blick auf zukünftige Entwicklungen weitere Nutzerwünsche und Nutzererwartungen erhoben.
Der UX-Design Workshop wurde erstmalig an der TU Chemnitz durchgeführt. Die im Rahmen dieser Studie erhobenen Daten werden an dieser Stelle veröffentlicht.
View lessCitizen Science, zu deutsch Bürgerwissenschaft, bezeichnet eine Form der wissenschaftlichen Forschung, bei der Bürgerinnen und Bürger aktiv an wissenschaftlichen Projekten teilnehmen. Die gesammelten Daten aus dem Citizen Science Teilprojekt einer Messkampagne von 2021 werden hier genauer beschrieben und zur Verfügung gestellt. Das meteorologische Bürgermessnetz gehörte zu einer groß angelegten Messkampagne, die unter dem Akronym FESSTVaL (Field Experiment on submesoscale spatio-temporal variability in Lindenberg) stattfand. Die Messkampagne wurde im Rahmen des vom Deutschen Wetterdienst (DWD) finanzierten Hans-Ertel-Zentrums für Wetterforschung (HErZ) initiiert. Sie fand in den Sommermonaten des Jahres 2021 am Meteorologischen Observatorium Lindenberg – Richard-Aßmann-Observatorium (MOL-RAO) des DWD südöstlich von Berlin statt. Um die Quellen sub-mesoskaliger Variabilität zu betrachten, konzentrierte sich die Messkampagne auf drei Hauptaspekte: Strukturen der atmosphärischen Grenzschicht, Cold Pools und Windböen. Ergänzend zu dem am Observatorium operationell betriebenen Messnetz und weiteren Messungen mittels professioneller Instrumente und dem von der Universität Hamburg entwickelten, gebauten und gewarteten temporären Stationsmessnetz (APOLLO) wurde im Rahmen der Kampagne der Mehrwert eines bürgerwissenschaftlichen Messnetzwerks untersucht. Die Geräte aus dem Bürgermessnetz wurden mit Technologien entwickelt, die das sogenannte ”Internet-of-things“ mit sich bringt. Desweiteren wurden kostengünstige Sensoren verbaut, um möglichst viele Geräte herstellen zu können. Die Geräte wurden als Bausätze ausgeteilt, die von Bürger*innen in wenigen Schritten zusammengebaut, aufgestellt und gewartet wurden.
View lessDieser Datensatz enthält Digitalisate der Feldtagebücher der Grabungsstelle "Gebäude P" (Grabungabschnitt „Tell“ (Zitadelle)) in Tall Šēḫ Ḥamad (Syrien) aus den Ausgrabungskampagnen 1978, 1980-1984, and 1987.
The netCDF file in the dataset includes grid information and the date of creation of the data on the High-Performance Computing (HPC) system. In this simulation with Re=1300 based on laminar Ekman layer thickness. We investigate the turbulent flow using a computational grid with dimensions of 2560 x 5120 x 640 and a spatial resolution of 8.9 × 4.5 × 0.99 in terms of wall units. The domain size is scaled to 0.54 in terms of Rossby radius. For detailed of the methodology and implementation, the git repository https://github.com/turbulencia/tlab contains the relevant code and a manual. This dataset also contains a PDF file outlining the simulation setup and description of the variables contained in the netCDF files.
View lessThe netCDF file in the dataset includes grid information and the date of creation of the data on the High-Performance Computing (HPC) system. In this simulation with Re=1000 based on laminar Ekman layer thickness. We investigate the turbulent flow using a computational grid with dimensions of 3072 x 6144 x 512 and a spatial resolution of 9.3 × 4.7 × 1.14 in term of wall units. The domain size is scaled to 1.08 in terms of the Rossby radius. For detailed of the methodology and implementation, the git repository https://github.com/turbulencia/tlab contains the relevant code and a manual. This dataset also contains a PDF file outlining the simulation setup and description of the variables contained in the netCDF files.
View lessThe netCDF file in the dataset includes grid information and the date of creation of the data on the High-Performance Computing (HPC) system. In this simulation with Re=1600 based on laminar Ekman layer thickness. We investigate the turbulent flow using a computational grid with dimensions of 3860 x 7680 x 960 and a spatial resolution of 8.6 × 4.3 × 1.00 in term of wall units. The domain size is scaled to 0.54 in terms of Rossby radius. For detailed of the methodology and implementation, the git repository https://github.com/turbulencia/tlab contains the relevant code and manual. This dataset also contains a PDF file outlining the simulation setup and description of the variables contained in the netCDF files.
View lessThe netCDF file in the dataset includes grid information and the date of creation of the data on the High-Performance Computing (HPC) system. In this simulation Re=500 based on laminar Ekman layer thickness. We investigate the turbulent flow using a computational grid with dimensions of 2048 x 2048 x 192 and a spatial resolution of 4.1 × 4.1 × 1.05 in terms of wall units. The domain size is scaled to 1.08 in terms of the Rossby radius. For details of the methodology and implementation, the git repository https://github.com/turbulencia/tlab contains the relevant code and a manual. This dataset also contains a PDF file outlining the simulation setup and description of the variables contained in the netCDF files.
View lessFour (4) samples of so-called Byzantine Globular Amphorae from the excavation of the rural farm at Ain Wassel (High Tunisian Tell) have been considered for organic residue analysis via gas chromatography-mass spectrometry (GC-MS) in order to better understand the function of this type of transport and storage container and shed new light on still poorly understood trade and consumption practices in Late Antique/Early Medieval North Africa. The content of this typological group of amphorae dating to the 7th-8th(?) century AD is still unknown. Following samples of the bottom of "anfora a fondo umbonato e ombelicato" (Maurina 2019), corresponding to the type Bonifay 65 (Bonifay 2004) have been analyzed in this study: Maurina 2019, Fig. 4.9, 14-17. The obtained results are available here in tabular form.
Bibliographic references:
Maurina, Barbara. “Contenitori Da Trasporto e per La Conservazione.” In Rus Africum IV: La Fattoria Bizantina Di Aïn Wassel, Africa Proconsularis (Alto Tell, Tunisia): Lo Scavo Stratigrafico e i Materiali, edited by Barbara Maurina and Mariette de Vos Raaijmakers, 245–94. Archaeopress, 2019. https://doi.org/10.2307/j.ctvndv6tz.8
Vos Raaijmakers, Mariette de, and Barbara Maurina, eds. Rus Africum IV: La Fattoria Bizantina Di Aïn Wassel, Africa Proconsularis (Alto Tell, Tunisia): Lo Scavo Stratigrafico e i Materiali. Archaeopress, 2019. https://doi.org/10.2307/j.ctvndv6tz
Bonifay M., Etudes sur la céramique Romaine Tardive d'Afrique, British Archaeological Reports, 2004
View lessThis is the supplementary material for the project "Countering the "Climate Cult" -- Framing Cascades in Far-right Digital Networks." We include our code in R Markdown format along with tables outlining the results of qualitative analyses and data cleaning. It also includes the Appendix, which features additional results and lists the dictionaries and intercoder reliability scores. The original dataset, needed to replicate the study and run the entire code, will be made available upon reasonable request to the corresponding author.
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